|
Mutation Information
|
Mutation Site
|
R539K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
AB033550
|
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
19431214
|
|
Disease
|
Occult HBV infection;
Hepatocellular carcinoma
|
|
Published Year
|
2009 |
|
Journal
|
International journal of cancer |
|
Title
|
A study on sequence variations in pre-S/surface, X and enhancer II/core promoter/precore regions of occult hepatitis B virus in non-B, non-C hepatocellular carcinoma patients in Taiwan. |
|
Author
|
Chen CH,Changchien CS,Lee CM,Tung WC,Hung CH,Hu TH,Wang JH,Wang JC,Lu SN |
|
Evidence
|
The amino acid substitution (G185R) in surface gene also caused an amino acid change at R539K in the overlapping reverse transcriptase (RT) domain of polymerase gene.
|
|
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HBV Mutation Detail Information