HBV Mutation Detail Information

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Mutation Information
Mutation Site M204I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Country Korea
Literature Information
PubMed PMID 24696492
Disease Chronic hepatitis B
Published Year 2014
Journal Journal of virology
Title The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene.
Author Ahn SH,Park YK,Park ES,Kim JH,Kim DH,Lim KH,Jang MS,Choe WH,Ko SY,Sung IK,Kwon SY,Kim KH
Evidence At viral breakthrough during LMV treatment, three conserved mutations (L80I, L199V, and M204I) were predominantly detected and colocalized on the same genome (the clone 22 series).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation