HBV Mutation Detail Information

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Mutation Information
Mutation Site H289N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country Argentina
Literature Information
PubMed PMID 25244642
Disease Chronic hepatitis B
Published Year 2014
Journal Journal of viral hepatitis
Title Hepatitis B virus depicts a high degree of conservation during the immune-tolerant phase in familiarly transmitted chronic hepatitis B infection: deep-sequencing and phylogenetic analysis.
Author Sede M,Lopez-Ledesma M,Frider B,Pozzati M,Campos RH,Flichman D,Quarleri J
Evidence In comparison with the other 29 complete sequences of genotype D1, 13 distinctive specific point mutations were observed in the nine complete genomes from the family as follows (amino acid changes at Polymerase): A544C (N474H), T996C,A1361T (Y746F), A1634G, G2648A, T2859C (S185P),C2928T (R208C), A2991G (S229G), A3000C (I232L),G3039A (G245L),and 3171A (H289N). C3083A (S259R), G3120A (K272E),and 3171A (H289N).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation