HBV Mutation Detail Information

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Mutation Information

Mutation Site	N139H
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	Mexico

Literature Information

PubMed PMID	25732900
Disease	HBV infection
Published Year	2015
Journal	Journal of medical virology
Title	New amino acid changes in drug resistance sites and HBsAg in hepatitis B virus genotype H.
Author	Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV
Evidence	Three additional amino acid changes were observed outside B‐Cell and T‐cell epitopes (Table IV, Fig. 1). Also, nine polymorphic changes were identified in the HBsAg domain; L8H, C19S/F, L21W, Q30R, S31N, S34L, C76Y, I208T, and Y221C; and four in the RT domain; H13Y, N139H, I163V, and I253R (Figs. 1 and 2).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation