|
Mutation Information
|
Mutation Site
|
L180P |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
24237431
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Mikrobiyoloji bulteni |
|
Title
|
[Investigation of baseline antiviral resistance in treatment-naive chronic hepatitis B cases]. |
|
Author
|
Ergünay K,Kahramanoğlu Aksoy E,Simşek H,Alp A,Sener B,Tatar G,Us D,Hasçelik G |
|
Evidence
|
Mutations conferring resistance to entecavir + lamivudine (S202G, M204V, L180M, T184N) were identified in one patient whereas L180P, A181Q and A194V substitutions associated with probable lamivudin + adefovir and tenofovir resistance, respectively, were detected in other patients.
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HBV Mutation Detail Information