HBV Mutation Detail Information

> L180M Search Result

Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204I+rt.L180M;rt.M204V+rt.L180M;rt.M204I+rt.L180M+rt.L80I;rt.M204V+rt.L180M+rt.L80I
Genotype/Subtype	B:C
Country	China

Literature Information

PubMed PMID	24992206
Disease	Chronic hepatitis B
Published Year	2015
Journal	Antiviral therapy
Title	Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.
Author	Li X,Liu Y,Zhao P,Wang Y,Chen L,Xin S,Zhang XX,Xu D
Evidence	Clonal sequencing identified 13 drug-resistant HBV strains: rtL80I+M204I, rtL80I+M204V, rtL180M+M204I, rtL180M+M204V, rtM204I, rtM204V, rtL80I+L180M+M204I, rtL80I+L180M+M204V, rtA181V, rtA181V+M204I, rtA181T+N236T, rtA181V+N236T and rtN236T.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation