Mutation Information
Mutation Site
|
M204V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.M204V+rt.M204I+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.M204I+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.M250L+rt.M204V+rt.M204I+s.C69*+rt.S78T;rt.N236T+rt.M204V+rt.A181T+rt.L180M+s.C69*+rt.S78T |
Country
|
China |
Literature Information
PubMed PMID
|
31398372
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2019 |
Journal
|
Antiviral research |
Title
|
Investigation of hepatitis B virus (HBV) rtS78T/sC69* mutation in a large cohort of chronic HBV-infected patients with nucleoside/nucleotide analogue treatment. |
Author
|
Luo D,Liu Y,Chen R,Niu M,Liu L,Li X,Li Q,Huang B,Wang J,Xu D,Lin S |
Evidence
|
For patient C, mutants rtL180M + T184A + M204V (48%), rtM204V (14%), rtS78T/sC69* + L180M + T184A (9%), rtS78T/sC69* + L180M + T184A + M204V (9%), rtS78T/sC69* (5%), and rtS78T/sC69* + M204V (5%) were detected in sample C1 at the end of ETV therapy.
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