HBV Mutation Detail Information

> M204I Search Result


Mutation Information
Mutation Site M204I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.L180M+rt.M204I+rt.T184A;rt.L180M+rt.M204I+rt.M204V+rt.T184A;rt.L180M+rt.M204I+rt.T184L;rt.L180M+rt.M204I+rt.M204V+rt.T184L;rt.L180M+rt.M204I+rt.M204V+rt.T184L+rt.T184A;rt.L180M+rt.M204I+rt.T184S;rt.L180M+rt.M204I+rt.M204V+rt.T184S;rt.L180M+rt.M204I+rt.T184S+rt.T184A;rt.L180M+rt.M204I+rt.T184I;rt.M204I+rt.T184I;rt.L180M+rt.M204I+rt.M204V+rt.T184I;rt.M204I+rt.M204V+rt.T184I;rt.L180M+rt.M204I+rt.S202G;rt.L180M+rt.M204I+rt.M204V+rt.S202G;rt.L180M+rt.M204I+rt.M250V;rt.L180M+rt.M204I+rt.M204V+rt.M250V;rt.L180M+rt.M204I+rt.M250L;rt.L180M+rt.M204I+rt.M204V+rt.M250L;rt.L180M+rt.M204I+rt.M250I;rt.L180M+rt.M204I+rt.M204V+rt.M250I;rt.L180M+rt.M204I+rt.M204V+rt.M250L+rt.M250V
Relevant Drug entecavir (ETV)
Country China
Literature Information
PubMed PMID 30866789
Disease HBV infection
Published Year 2019
Journal Emerging microbes & infections
Title Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice.
Author Liu Y,Zhou Y,Li X,Niu M,Chen R,Shao J,Si L,Luo D,Lin Y,Li L,Zhang K,Xiao X,Xu Z,Liu M,Lu M,Zoulim F,Xu D
Evidence Entecavir (ETV) resistance of hepatitis B virus (HBV) conventionally requires rt184, 202, or 250 mutations plus lamivudine-resistance mutation (rtM204V/I +- L180M).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation