HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A2
Viral Reference	X70185.1
Relevant Drug	lamivudine (LAM);adefovir (ADV);entecavir (ETV)

Literature Information

PubMed PMID	22453135
Disease	Chronic hepatitis B
Published Year	2012
Journal	Antiviral research
Title	Long-term monitoring drug resistance by ultra-deep pyrosequencing in a chronic hepatitis B virus (HBV)-infected patient exposed to several unsuccessful therapy schemes.
Author	Sede M,Ojeda D,Cassino L,Westergaard G,Vazquez M,Benetti S,Fay F,Tanno H,Quarleri J
Evidence	Under sequential HBV monotherapies including lamivudine, adefovir and entecavir, a high frequency of rtM204I mutation was detected initially as unique and then coexisting with rtM204V.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation