|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204L+rt.L180M |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
15338371
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2004 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
Prognostic indicators of breakthrough hepatitis during lamivudine monotherapy for chronic hepatitis B virus infection. |
|
Author
|
Tanaka Y,Yeo AE,Orito E,Ito K,Hirashima N,Ide T,Sata M,Mizokami M |
|
Evidence
|
Univariate statistical analyses showed that possible prognostic indicators for the occurrence of BTH were pre-S deletions ( P = 0.03) and L180M/M204L mutations ( P = 0.04).
|
|
|
HBV Mutation Detail Information