|
Mutation Information
|
Mutation Site
|
A181G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
D/D4 |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);adefovir dipivoxil (ADV);tenofovir (TNF) |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
23918533
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Journal of medical virology |
|
Title
|
Hepatitis B virus reverse transcriptase mutations in treatment Naïve chronic hepatitis B patients. |
|
Author
|
Singla B,Chakraborti A,Sharma BK,Kapil S,Chawla YK,Arora SK,Das A,Dhiman RK,Duseja A |
|
Evidence
|
The ADV‐related resistance mutation (rtI233V) was found in two patients, and one patient displayed the rtA181G mutation related to LMV, LdT, ADV, and TNF resistance.
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HBV Mutation Detail Information