|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.L80V+rt.M204V |
|
Viral Reference
|
AB033550.1
|
|
Relevant Drug
|
interferon(IFN) |
Literature Information
|
PubMed PMID
|
17352033
|
|
Disease
|
HBV infection
|
|
Published Year
|
2007 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Fatal liver failure caused by reactivation of lamivudine-resistant hepatitis B virus: a case report. |
|
Author
|
Suzuki Y,Yotsuyanagi H,Okuse C,Nagase Y,Takahashi H,Moriya K,Suzuki M,Koike K,Iino S,Itoh F |
|
Evidence
|
After the start of antiviral treatment, rtL180M was detected in addition to rtM204I/V and rtL80I/V, and became predominant in the terminal stage of the disease.
|
|
|
HBV Mutation Detail Information