|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.V173L+rt.M204V, rt.L180M+rt.M204V+rt.S202I |
|
Genotype/Subtype
|
E |
|
Viral Reference
|
X75657
|
|
Relevant Drug
|
lamivudine |
|
Country
|
Nigeria |
Literature Information
|
PubMed PMID
|
33446224
|
|
Clinical information
|
Yes
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2021 |
|
Journal
|
Virology journal |
|
Title
|
Prevalence and characteristics of hepatitis B and D virus infections among HIV-positive individuals in Southwestern Nigeria. |
|
Author
|
Opaleye OO,Akanbi OA,Osundare FA,Wang B,Adesina O,Oluremi AS,Sunday ST,Akindele AA,Klink P,Bock CT |
|
Evidence
|
HBV DRMs V173L, L180M, S202I and M204V/I, which are associated with lamivudine resistance, were detected in 32.2% (n = 10/31) of the HBV DNA-positive samples.
|
|
|
HBV Mutation Detail Information