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Mutation Information
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Mutation Site
|
L577M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
P |
Literature Information
|
PubMed PMID
|
14752824
|
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Disease
|
Chronic hepatitis B
|
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Published Year
|
2004 |
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Journal
|
Hepatology (Baltimore, Md.) |
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Title
|
Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. |
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Author
|
Ciancio A,Smedile A,Rizzetto M,Lagget M,Gerin J,Korba B |
|
Evidence
|
Q130P (Q478R)25 was present in all 26 patients, S211N (S559N)27 and S219A (S567A)29 were observed in 4 patients, L82M (L430M)2 and L229M/V (L577M/V)24, 29 were present in a non‐responder (#11), and Q215H26 was found in 1 breakthrough patient (#13).
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HBV Mutation Detail Information