HBV Mutation Detail Information

> A181V Search Result


Mutation Information
Mutation Site A181V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug lamivudine (LAM)
Country Japan
Literature Information
PubMed PMID 21503906
Disease Chronic hepatitis B
Published Year 2011
Journal Journal of medical virology
Title Clinical course and predictive factors of virological response in long-term lamivudine plus adefovir dipivoxil combination therapy for lamivudine-resistant chronic hepatitis B patients.
Author Aizawa M,Tsubota A,Fujise K,Tatsuzawa K,Kono M,Hoshina S,Tajiri H
Evidence Breakthrough hepatitis occurred in three patients without complete viral response and with poor response to the preceding LAM monotherapy, and rtA181A/V substitution was detected in one of the three patients.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation