|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
25287170
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
Gut and liver |
|
Title
|
Long-term outcomes and dynamics of mutants associated with lamivudine-adefovir rescue therapy in patients with lamivudine-resistant chronic hepatitis B. |
|
Author
|
Kim J,Lee SH,Kim HS,Choi K,Jeong SW,Kim SG,Jang JY,Kim YS,Kim BS |
|
Evidence
|
The baseline mutation profiles, rtM204I (p=0.992), rtM204I/V (p=0.177), and rtL180M (p=0.051), were not correlated with the cumulative virological response, and the baseline HBV DNA level (p=0.032) was the only independent predictive factor for cumulative virological response.
|
|
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HBV Mutation Detail Information