|
Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.V173L+rt.L180M+rt.M204V |
|
Country
|
Belgium |
Literature Information
|
PubMed PMID
|
20087936
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis
|
|
Published Year
|
2010 |
|
Journal
|
Journal of medical virology |
|
Title
|
Molecular evolutionary analysis and mutational pattern of full-length genomes of hepatitis B virus isolated from Belgian patients with different clinical manifestations. |
|
Author
|
Pourkarim MR,Amini-Bavil-Olyaee S,Verbeeck J,Lemey P,Zeller M,Rahman M,Maes P,Nevens F,Van Ranst M |
|
Evidence
|
Six out of 13 treated patients with lamivudine developed mutations associated with lamivudine resistance in the HBV reverse transcriptase region comprising rtM204V, rtM204V+rtL180M, and rtM204V+rtL180M+rtV173L.
|
|
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HBV Mutation Detail Information