Mutation Information
Mutation Site
|
V173L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.C188L+rt.V173L;rt.V173L+rt.I169V;rt.M204V+rt.L180M+rt.V173L;rt.M204V+rt.L180M+rt.V173L+rt.I169V;rt.M204V+rt.L180M+rt.V173L+rt.H35N;rt.M204V+rt.L180M+rt.V173L+rt.H35N |
Relevant Drug
|
lamivudine (LAM);entecavir (ETV);adefovir dipivoxil (ADV);tenofovir (TDF);telbivudine (LDT) |
Literature Information
PubMed PMID
|
30202825
|
Disease
|
HBV infection
|
Published Year
|
2018 |
Journal
|
Hepatology communications |
Title
|
Discovery of the Novel Entecavir-Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis. |
Author
|
Rose RE,Hernandez D,Falk PJ,Ericson K,Zhou N,Thiry A,McPhee F |
Evidence
|
Table2
|
|
|