HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	adefovir (ADV)
Country	Spain

Literature Information

PubMed PMID	17988612
Disease	Chronic hepatitis B
Published Year	2007
Journal	Medicina clinica
Title	[Adefovir dipivoxil compassionate use program in Spain: efficacy and resistance analysis].
Author	Buti M,Rodríguez Frías F,Calleja JL,Jardí R,Pons F,Crespo J,Casanovas T,Enríquez J,Carnicer F,Romero M,García Bengoechea M,Prieto M,García Samaniego J,Miras M,Pérez Roldán F,Rueda M,Esteban R
Evidence	20% patients developed resistance to adefovir dipivoxil, and the most frequent detected mutations were: A181V, A181T and N236T.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation