HBV Mutation Detail Information

> M204V Search Result

Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Relevant Drug	lamivudine (LAM)
Country	Korea

Literature Information

PubMed PMID	20332649
Disease	Chronic hepatitis B
Published Year	2010
Journal	Intervirology
Title	Response to adefovir depends on mutation patterns in precore region, basal core promoter and reverse transcriptase, and on-treatment responses in Lamivudine-resistant chronic hepatitis B patients.
Author	Song BC,Cui XJ,Shin JW,Park NH,Cho YK,Song HJ,Hyun S,Jeong SU,Choi EK,Kim HU
Evidence	RtM204I, rtM204V, rtM204I/V mutations and the wild type were found in 36 patients (54.5%), 25 patients (37.9%), 4 patients (6.1%) and 1 patient (1.5%), respectively, prior to adefovir therapy.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation