|
Mutation Information
|
Mutation Site
|
L526M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
10502255
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
1999 |
|
Journal
|
Journal of medical virology |
|
Title
|
Novel patterns of amino acid mutations in the hepatitis B virus polymerase in association with resistance to lamivudine therapy in japanese patients with chronic hepatitis B. |
|
Author
|
Ogata N,Fujii K,Takigawa S,Nomoto M,Ichida T,Asakura H |
|
Evidence
|
A substitution of methionine for leucine at residue 526 (L526M) has also been identified.
|
|
|
HBV Mutation Detail Information