HBV Mutation Detail Information

> M550I Search Result


Mutation Information
Mutation Site M550I
Mutation Type Amino acid level
Gene/Protein/Region Type P
Relevant Drug famciclovir (FCV);lamivudine (LAM)
Country china
Literature Information
PubMed PMID 11792996
Disease Chronic hepatitis B
Published Year 2002
Journal Transplantation
Title Efficacy of famciclovir in the treatment of lamivudine resistance related to an atypical hepatitis B virus mutant.
Author Tang S,Ho SK,Moniri K,Lai KN,Chan TM
Evidence The severe hepatitic flare consequent to the lamivudine resistance in this patient was successfully treated with famciclovir, indicating that both M550V and M550I mutants with preserved wild-type sequence at position 526 of HBV reverse transcriptase are susceptible to famciclovir.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation