HBV Mutation Detail Information

> I169L Search Result


Mutation Information
Mutation Site I169L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype A
Viral Reference X02763
Country Asia‐Pacific;Europe
Literature Information
PubMed PMID 32579776
Disease Chronic hepatitis B
Published Year 2020
Journal Journal of viral hepatitis
Title Virology analysis of chronic hepatitis B virus-infected patients treated for 28 days with JNJ-56136379 monotherapy.
Author Verbinnen T,Hodari M,Talloen W,Berke JM,Blue D,Yogaratnam J,Vandenbossche J,Shukla U,De Meyer S,Lenz O
Evidence One placebo‐treated patient (HBeAg‐negative, GT‐D) had emerging I169L mutation at day 29 (sequence‐read frequency of 67%) which decreased again in frequency at follow‐up week 12 (19%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation