Mutation Information
Mutation Site
|
Q215S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
Turkey |
Literature Information
PubMed PMID
|
22224083
|
Disease
|
HBV infection
|
Published Year
|
2011 |
Journal
|
Hepatitis monthly |
Title
|
Frequency and mutation patterns of resistance in patients with chronic hepatitis B infection treated with nucleos(t)ide analogs in add-on and switch strategies. |
Author
|
Sayan M,Akhan SC,Senturk O |
Evidence
|
Single compensatory mutations were not detected in the switch therapy group; however, rtQ215H/P/S +- rtV214A/P mutations were found in 12 out of 88 patients (14%) in the add-on therapy group, and this difference was significant (P < 0.03).
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