Mutation Information
Mutation Site
|
A1758C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
P |
Nucleotide_Mutation
|
N248H |
Relevant Drug
|
tenofovir (TDF) |
Country
|
Pakistan |
Literature Information
PubMed PMID
|
30285571
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2018 |
Journal
|
Viral immunology |
Title
|
Predictors of Therapeutic Outcome to Nucleotide Reverse Transcriptase Inhibitor in Hepatitis B Patients. |
Author
|
Aziz M,Aziz H,Waheed Y,Gill ML |
Evidence
|
We noted that nonresponder patients showed substitution asparagine to histidine in E motif at rt248 amino acid positions (rtN248H mutation; nucleotide substitution from A to C at 1758 bp position) (Fig. 4).
|
|
|