HBV Mutation Detail Information

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Mutation Information
Mutation Site A1758C
Mutation Type Nucleotide level
Gene/Protein/Region Type P
Nucleotide_Mutation N248H
Relevant Drug tenofovir (TDF)
Country Pakistan
Literature Information
PubMed PMID 30285571
Disease Chronic hepatitis B
Published Year 2018
Journal Viral immunology
Title Predictors of Therapeutic Outcome to Nucleotide Reverse Transcriptase Inhibitor in Hepatitis B Patients.
Author Aziz M,Aziz H,Waheed Y,Gill ML
Evidence We noted that nonresponder patients showed substitution asparagine to histidine in E motif at rt248 amino acid positions (rtN248H mutation; nucleotide substitution from A to C at 1758 bp position) (Fig. 4).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation