HBV Mutation Detail Information

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Mutation Information

Mutation Site	N139H
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	adefovir dipivoxil (ADV)
Country	Korea

Literature Information

PubMed PMID	19578241
Disease	Chronic hepatitis B
Published Year	2009
Journal	Antiviral therapy
Title	Adefovir dipivoxil resistance patterns in patients with lamivudine-resistant chronic hepatitis B.
Author	Santantonio T,Fasano M,Durantel S,Barraud L,Heichen M,Guastadisegni A,Pastore G,Zoulim F
Evidence	In one of the two patients with primary treatment failure, the following mutation pattern was observed before adding ADV:rtL180M, rtM204I/V, rtV173L, rtR138K, rtN139H,S219A, F221Y and rtL229F.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation