HBV Mutation Detail Information

> N238D Search Result


Mutation Information
Mutation Site N238D
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B
Viral Reference Y1855; DQ448619.1
Country China
Literature Information
PubMed PMID 22138714
Disease Chronic hepatitis B
Published Year 2012
Journal Antiviral research
Title Prevalence, virology and antiviral drugs susceptibility of hepatitis B virus rtN238H polymerase mutation from 1865 Chinese patients with chronic hepatitis B.
Author Zhong Y,Lv J,Li J,Xing X,Zhu H,Su H,Chen L,Zhou X
Evidence Among 1865 enrolled HBV infected patients, 8.8% (165/1865) showed mutations in the rtN238 locus (143 males/22 females, 91 treatment-naive, 42 ADV-treated, 16 LAM-treated and 16 ADV+LAM-treated), namely 86% rtN238H (142/165), 5.5% rtN238S (9/165), 5.5% rtN238T (9/165) and 3% rtN238D (5/165).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation