|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M+rt.V173L |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Italian |
Literature Information
|
PubMed PMID
|
19475624
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2009 |
|
Journal
|
Journal of medical virology |
|
Title
|
Effect of HIV co-infection on mutation patterns of HBV in patients with lamivudine-resistant chronic hepatitis B. |
|
Author
|
Iacomi F,Vincenti D,Vairo F,Solmone M,Mariano A,Piselli P,Puro V,Capobianchi MR,Antonucci G |
|
Evidence
|
In this latter group, the prevalence of the rtV173L + rtL180M + rtM204V triple mutation was 31% versus a prevalence of 3.4% observed among patients infected with HBV only.
|
|
|
HBV Mutation Detail Information