HBV Mutation Detail Information

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Mutation Information
Mutation Site L173V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204V+rt.L180M+rt.L173V
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 16549970
Disease HBV-HIV coinfection
Published Year 2006
Journal AIDS (London, England)
Title Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy.
Author Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL
Evidence The triple polymerase mutant (rtL173V, rtL180M, rtM204V), which behaves as a vaccine escape mutant in vitro, occurred in 17% of viraemic patients.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation