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Mutation Information
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Mutation Site
|
V253I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
|
rt.V207M+rt.V253I;rt.N238A+rt.V253I |
|
Country
|
Vietnam |
Literature Information
|
PubMed PMID
|
32708399
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Diagnostics (Basel, Switzerland) |
|
Title
|
COLD-PCR Method for Early Detection of Antiviral Drug-Resistance Mutations in Treatment-Naive Children with Chronic Hepatitis B. |
|
Author
|
Phung TTB,Chu SV,Vu ST,Pham HT,Nguyen HM,Nguyen HD,Le NT,Nguyen DV,Truong PT,Vu VTT,Nguyen ATV |
|
Evidence
|
Among these above 94 cases, there were 11 cases carrying additional mt that are not related to drug resistance, such as rtI187V (+ rtV207M) × 2 cases, rtI187V (+ rtS213T), rtI187V (+ rtP237T), rtI187V (+ rtL229V), rtI187V (+ rtV207M + rtS213T + rtS256G), rtK212T (+ rtV207I + rtV207M), rtV253I (+ rtV207M), rtV253I (+ rtN238A) × 2 cases, and rtL235V (+ rtV207M + rtL229V).
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HBV Mutation Detail Information