HBV Mutation Detail Information

> M204I Search Result

Mutation Information

Mutation Site	M204I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.L180M+rt.M204I;rt.V173L+rt.M204I;rt.V207I+rt.M204I;rt.V173L+rt.L180M+rt.M204I;rt.V207I+rt.L180M+rt.M204I;rt.V207I+rt.V173L+rt.M204I;rt.V207I+rt.V173L+rt.L180M+rt.M204I
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	16378967
Disease	HBV infection
Published Year	2006
Journal	Journal of virology
Title	Dynamics of hepatitis B virus resistance to lamivudine.
Author	Pallier C,Castéra L,Soulier A,Hézode C,Nordmann P,Dhumeaux D,Pawlotsky JM
Evidence	Virological breakthrough was preceded by 2 to 4 months by the emergence of quasispecies variants bearing amino acid substitutions at RT position 204, i., within the YMDD catalytic motif (rtM204V/I).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation