|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
21396961
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
Journal of virological methods |
|
Title
|
HBV DNA replication mediated by cloned patient HBV reverse transcriptase genes from HBV genotypes A-H and its use in antiviral phenotyping assays. |
|
Author
|
Zhu Y,Curtis M,Borroto-Esoda K |
|
Evidence
|
Similarly, patient derived RT genes containing the adefovir resistance (ADV-R) mutations rtA181V or rtN236T demonstrated an ADV-R phenotype.
|
|
|
HBV Mutation Detail Information