|
Mutation Information
|
Mutation Site
|
M550V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Combined Mutation
|
p.M550V+p.L526M |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
16004082
|
|
Published Year
|
2005 |
|
Journal
|
Antiviral chemistry & chemotherapy |
|
Title
|
Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative. |
|
Author
|
Li Y,Fu L,Yeo H,Zhu JL,Chou CK,Kou YH,Yeh SF,Gullen E,Austin D,Cheng YC |
|
Evidence
|
The lamivudine-resistant HBV, L526M/M550V double mutant strain, was also sensitive to helioxanthin and 5-4-2.
|
|
|
HBV Mutation Detail Information