|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.M204I+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.M204I+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.M204V+rt.T184A+rt.L180M+s.C69*+rt.S78T;rt.N236T+rt.M204V+rt.A181T+rt.L180M+s.C69*+rt.S78T |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31398372
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2019 |
|
Journal
|
Antiviral research |
|
Title
|
Investigation of hepatitis B virus (HBV) rtS78T/sC69* mutation in a large cohort of chronic HBV-infected patients with nucleoside/nucleotide analogue treatment. |
|
Author
|
Luo D,Liu Y,Chen R,Niu M,Liu L,Li X,Li Q,Huang B,Wang J,Xu D,Lin S |
|
Evidence
|
For patient C, mutants rtL180M + T184A + M204V (48%), rtM204V (14%), rtS78T/sC69* + L180M + T184A (9%), rtS78T/sC69* + L180M + T184A + M204V (9%), rtS78T/sC69* (5%), and rtS78T/sC69* + M204V (5%) were detected in sample C1 at the end of ETV therapy.
|
|
|
HBV Mutation Detail Information