HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	25318660
Disease	Chronic hepatitis B
Published Year	2015
Journal	Journal of gastroenterology and hepatology
Title	Incidence of natural resistance mutations in naïve chronic hepatitis B patients: a systematic review and meta-analysis.
Author	Zhang Q,Liao Y,Cai B,Li Y,Li L,Zhang J,An Y,Wang L
Evidence	Among all the primary mutations, rtM204V/I ranked the first with the highest summarized incidence of mutations 4.85% (95%CI: 4.09–5.60%), which was far more than the pooled rate of rtS202I/G/R, rtA181T/V, and rtA194T (incidence: 0.51% [95%CI: 0–1.16%], 0.40% [95%CI: 0–0.79%], and 0.37% [95%CI: 0–0.74%], respectively).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation