HBV Mutation Detail Information

> N236T Search Result


Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.N236T+rt.A181T
Relevant Drug adefovir (ADV)
Country Japan
Literature Information
PubMed PMID 18433925
Disease Chronic hepatitis B
Published Year 2008
Journal Journal of hepatology
Title Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up.
Author Yatsuji H,Suzuki F,Sezaki H,Akuta N,Suzuki Y,Kawamura Y,Hosaka T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Watahiki S,Iwasaki S,Kobayashi M,Kumada H
Evidence In the remaining 129 patients, the rtM204 mutants were identified at baseline, and two (1.6%) of the 129 patients developed new ADV-resistant mutants; one was rtA181S and another was rtA181T plus rtN236T mutation

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation