HBV Mutation Detail Information

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Mutation Information

Mutation Site	N236T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.N236T+rt.M204V
Genotype/Subtype	D
Country	Rome

Literature Information

PubMed PMID	19442845
Disease	Chronic hepatitis B
Published Year	2009
Journal	Journal of virological methods
Title	A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations.
Author	Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR
Evidence	The same DR v2 test detected only M204I in a sample composed of a mixture of wild type and M204I, seen by direct sequencing, and a mixture of wild type + M204V + N236T in another sample, while direct sequencing detected wild type + M204V + L180M; again, in one sample from an HIV positive patient DR v2 detected only M204V, while direct sequencing detected M204V + L180M.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation