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Mutation Information
|
Mutation Site
|
N238K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Thailand |
Literature Information
|
PubMed PMID
|
22860080
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Long-term hepatitis B virus (HBV) response to lamivudine-containing highly active antiretroviral therapy in HIV-HBV co-infected patients in Thailand. |
|
Author
|
Khamduang W,Gaudy-Graffin C,Ngo-Giang-Huong N,Jourdain G,Moreau A,Luekamlung N,Halue G,Buranawanitchakorn Y,Kunkongkapan S,Buranabanjasatean S,Lallemant M,Sirirungsi W,Goudeau A,Program for HIV Prevention and Treatment Study Group. |
|
Evidence
|
The ntT843G mutation of unknown significance was also observed and resulted in the change from asparagine to lysine in the reverse transcriptase protein (rtN238K).
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HBV Mutation Detail Information