HBV Mutation Detail Information

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Mutation Information
Mutation Site L180M
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204I+rt.M204V+rt.L180M
Genotype/Subtype A;D;F
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 15918335
Disease HBV infection
Published Year 2005
Journal Antiviral therapy
Title Evaluation of methods for monitoring drug resistance in chronic hepatitis B patients during lamivudine therapy based on mass spectrometry and reverse hybridization.
Author Kim HS,Han KH,Ahn SH,Kim EO,Chang HY,Moon MS,Chung HJ,Yoo W,Kim SO,Hong SP
Evidence A total of 60 patient samples were analysed for the presence of mutations at rtL1 80M and rtM204I/V of HBV polymerase by the LiPA and RFMP assays.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation