|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);entericavir;telbivudine (LDT);tenofovir (TDF) |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
33245644
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2020 |
|
Journal
|
Klinicheskaia laboratornaia diagnostika |
|
Title
|
Optimization of the algorithm diagnosis chronic hepatitis B markers in patients with newly diagnosed HIV infection. |
|
Author
|
Semenov AV,Ostankova YV,Serikova EN,Zueva EB,Totolian AA |
|
Evidence
|
Three HBV isolates (8.3%) were identified with drug resistance mutations to lamivudine, entericavir, telbivudine and tenofovir, which are amino acid substitutions in the HBV polymerase gene at positions L180M, T184A, M204V.
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HBV Mutation Detail Information