|
Mutation Information
|
Mutation Site
|
A422A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Combined Mutation
|
s.I68T+p.A422A |
|
Viral Reference
|
AB033550
|
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
18939932
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2008 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: a case-control study. |
|
Author
|
Chen CH,Changchien CS,Lee CM,Hung CH,Hu TH,Wang JH,Wang JC,Lu SN |
|
Evidence
|
Multivariate analysis showed that pre-S deletions, I68T surface gene, T1762/A1764, and A1899 were independent factors associated with the development of HCC.
|
|
|
HBV Mutation Detail Information