|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
24930916
|
|
Disease
|
Acute hepatitis B
|
|
Published Year
|
2014 |
|
Journal
|
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |
|
Title
|
Clinical and virological characteristics associated with severe acute hepatitis B. |
|
Author
|
Coppola N,Sagnelli C,Pisaturo M,Minichini C,Messina V,Alessio L,Starace M,Signoriello G,Gentile I,Filippini P,Sagnelli E |
|
Evidence
|
The HBV mutants in the polymerase region were sought in 110 (87%) patients by direct sequencing, and the rtM204V/I mutations also by an allele-specific PCR.
|
|
|
HBV Mutation Detail Information