|
Mutation Information
|
Mutation Site
|
M250M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
entecavir (ETV) |
Literature Information
|
PubMed PMID
|
18070286
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Hepatitis B virus polymerase variants associated with entecavir drug resistance in treatment-naive patients. |
|
Author
|
Jardi R,Rodriguez-Frias F,Schaper M,Ruiz G,Elefsiniotis I,Esteban R,Buti M |
|
Evidence
|
The rtS202S/I variant was found in six cases (two in conjunction with rtI169I/T and one with rtT184A),rtT184T/A in two cases, rtM250 M/V in one case and the remaining patient initially showed the rtI169I/T variant.
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HBV Mutation Detail Information