HBV Mutation Detail Information

> T184A Search Result


Mutation Information
Mutation Site T184A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B;C
Relevant Drug entecavir (ETV)
Country China
Literature Information
PubMed PMID 26612031
Disease HBV infection
Published Year 2015
Journal Scientific reports
Title Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China.
Author Zhang Q,Liao Y,Chen J,Cai B,Su Z,Ying B,Lu X,Tao C,Wang L
Evidence As shown in Table 2, ADV-associated mutation rtA181V/T/S demonstrated a remarkable higher prevalence in genotype C than genotype B (13.5% vs. 5.1%, P < 0.001), and so did other mutations (rtN/H238T P < 0.001, rtP237H P = 0.002, and rtV214A P = 0.006). Nevertheless, LMV-associated mutation rtM204V/I and rtL180M, LdT-associated mutation rtM204I, and ETV-associated mutations rtT184A/I/S, rtS202G and rtM250L didn’t differ significantly between genotype B and C (P > 0.05).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation