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Mutation Information
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Mutation Site
|
A181V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.A186T+rt.A181V |
|
Country
|
China |
Literature Information
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PubMed PMID
|
30796932
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
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Journal
|
Antiviral research |
|
Title
|
Prevalence of the entecavir-resistance-inducing mutation rtA186T in a large cohort of Chinese hepatitis B virus patients. |
|
Author
|
Liu L,Liu Y,Chen R,Li X,Luo D,Zhao Y,Li Q,Huang B,Wang FS,Liu X,Xu D |
|
Evidence
|
In sample D1 at baseline and sample D2 at month 15, the rtA181V mutation was predominantly detected. VBT occurred at month 49 and two rtL180M+A186T+M204V mutants, rtL180M+A186T+M204V (95%) and rtL180M+A186T+M204V+M250V (5%), were detected in sample D3.
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HBV Mutation Detail Information