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Mutation Information
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Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+prec.G1896A |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
17573951
|
|
Disease
|
HBV infection
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology research : the official journal of the Japan Society of Hepatology |
|
Title
|
Changes in viral loads of lamivudine-resistant mutants during entecavir therapy. |
|
Author
|
Suzuki F,Suzuki Y,Akuta N,Yatsuji H,Sezaki H,Arase Y,Kawamura Y,Hosaka T,Kobayashi M,Ikeda K,Kobayashi M,Watahiki S,Kumada H |
|
Evidence
|
We investigated viral load changes of YMDD mutant virus (rtM204I [YIDD sequence], rtM204V [YVDD]) in serial serum samples during entecavir treatment for lamivudine-resistant virus and determined changes in viral precore and core promoter mutants.
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HBV Mutation Detail Information