HBV Mutation Detail Information

> G700A Search Result

Mutation Information

Mutation Site	G700A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	RT
Combined Mutation	rt.V191I+s.W182*
Nucleotide_Mutation	V191I
Genotype/Subtype	D
Relevant Drug	lamivudine (LAM)
Country	India

Literature Information

PubMed PMID	16428891
Disease	Chronic hepatitis B
Published Year	2006
Journal	Intervirology
Title	Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India.
Author	Kazim SN,Sarin SK,Sharma BC,Khan LA,Hasnain SE
Evidence	Inter-estingly, the same patient had another stop codon at aa 182 (sW182St.) in the surface gene ( fi g. 1 , table 4 ), which was due to rtV191I substitution in the polymerase gene. This patient also developed hepatocellular carcinoma and died eventually ( table 4 ).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation