HBV Mutation Detail Information

> A181T Search Result


Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Amino acid_Mutation G670A
Relevant Drug adefovir (ADV)
Country china
Literature Information
PubMed PMID 32840739
Disease Chronic hepatitis B
Published Year 2020
Journal Virus genes
Title An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene.
Author Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J
Evidence Mutation(s) in the polymerase gene responsible for ADV resistance included rtA181T (all clones) and rtN236T (four clones).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation