HBV Mutation Detail Information

> M204V Search Result


Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204V+rt.L180M+rt.V173L
Viral Reference X02763
Relevant Drug lamivudine (LAM)
Country USA
Literature Information
PubMed PMID 23454647
Disease HBV infection
Published Year 2013
Journal Journal of virological methods
Title Combination of allele-specific detection techniques to quantify minority resistance variants in hepatitis B infection: a novel approach.
Author Bhattacharya D,Lewis MJ,Lassmann B,Phan T,Knecht G,Bickel M,Yang OO
Evidence Detection of minor variant viral quasispecies of the rtV173L+rtL180M+rtM204V combination mutation in the hepatitis B virus (HBV) polymerase mediating both lamivudine resistance and vaccine escape is potentially important for tracking the development and evolution of resistance within both individuals and populations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation