HBV Mutation Detail Information

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Mutation Information
Mutation Site V214A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country china
Literature Information
PubMed PMID 33124952
Disease Chronic hepatitis B
Published Year 2020
Journal Emerging microbes & infections
Title Mutational characterization of HBV reverse transcriptase gene and the genotype-phenotype correlation of antiviral resistance among Chinese chronic hepatitis B patients.
Author Fu Y,Wu S,Hu Y,Chen T,Zeng Y,Liu C,Ou Q
Evidence Putative resistance mutations were observed at 8 AA sites among the panel of treatment-naive patients; they were rtV191I, rtS213T, rtV214A, rtE218D, rtL229V, rtI233V, rtN238S, rtS/C256G. The classical NA-r mutations rtL180M (ntT/C667A) and rtM204V/I (ntA739G or ntG741T/A), were treatment-specific and were preferentially present in post-treatment patients.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation